Organic Acids and Nutritional Testing

Organic acids are metabolic bi-products that are produced in the body’s production of  energy, detoxification, neurotransmitter conversion and breakdown, or intestinal microbial activity. Elevation of specific organic acids detected in urine often indicates a metabolic block or inhibition. The metabolic block may be due to a nutrient deficiency, an  enzyme deficit, toxic build-up or effect of drugs. Also there are also biomarkers of intestinal bacterial or yeast overgrowth.

The Organix Comprehensive nutritional test by Genova Diagnostics profile provides valuable information from a simple urine specimen. This organic acids nutritional test is very helpful for determining:

  • Functional vitamin and mineral status
  • Amino acid deficiencies such as carnitine and NAC
  • Oxidative damage and antioxidant need
  • Phase I & Phase II detoxification function
  • Functional B-complex vitamin need
  • Neurotransmitter status
  • Mitochondrial energy production
  • Methylation capability
  • Lipoic acid and CoQ10 status
  •  bacterial and yeast overgrowth

 

2-Methylhippurate
3,4 Dihydroxyphenylpropionate
5-hydroxyindoleacetate
8-Hydroxy-2′-deoxyguanosine*

Adipate
Alpha-Hydroxybutyrate
Alpha-Keto-Beta-Methylvalerate
Alpha-Ketoglutarate
Alpha-Ketoisocaproate
Alpha-Ketoisovalerate
Benzoate
Beta-Hydroxybutyrate
Beta-Hydroxyisovalerate
Citrate
Creatinine
D-Arabinitol*
D-Lactate*
Ethylmalonate
Formiminoglutamate
Fumarate
Glucarate
Hippurate
Homvanillate
Hydroxymethylglutarate
Indican
Isocitrate
Kynurenate
L-Lactate*
Malate
Methylmalonate
Orotate
Phenylacetate
Phenylpropionate
Picolinate*
Pyroglutamate
Pyruvate
Quinolinate
Suberate
Succinate
Sulfate
Tricarballylate
Vanilmandelate
Xanthurenate
cis-Aconitate
p-Hydroxybenzoate
p-Hydroxyphenylacetate
p-Hydroxyphenyllactate